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Loneliness Linked to Preclinical Alzheimer’s Disease

Peter Brissette • November 14, 2016

 Loneliness in cognitively normal older adults may actually be an early manifestation of Alzheimer’s disease, according to new research based on data from the Harvard Aging Brain Study.

Loneliness may be associated with significant amyloid deposits, “suggesting that loneliness is a neuropsychiatric symptom relevant to preclinical Alzheimer’s disease,” reports MedPage Today.

People who were classified as amyloid-positive were 75 times more likely to identify themselves as lonely sometimes or often than those who were amyloid-negative.

The link between higher amyloid levels and loneliness was stronger in older adults who carry a gene with a high Alzheimer’s disease risk factor than those without that gene. “Loneliness, characterized by subtle feelings of social detachment, may be associated with early brain changes in preclinical Alzheimer disease, prior to mild cognitive impairment,” write the researchers.

Source: http://www.argentum.org/News/5242/Loneliness%2DLinked%2Dto%2DPreclinical%2DAlzheimers%2DDisease


By Paul Trusik September 12, 2025
Reminiscence therapy, which encourages seniors in assisted living to revisit memories and share personal life stories, can offer profound emotional benefits. Cognitive abilities might change as people age, but memories often remain vivid, offering a powerful connection to their past and sense of identity. Reminiscence therapy allows seniors to process their experiences and emotions, improving their emotional well-being and quality of life. Additionally, it allows seniors to build connections with others, strengthening their social bonds.  Many assisted living communities have recognized the positive impacts of reminiscence therapy. Not only does it help with emotional expression, but it also improves cognitive function and strengthens mental resilience. Revisiting memories brings joy, stimulates mental activity, and creates a greater sense of purpose among seniors. The Impact of Reminiscence Therapy on Cognitive Health Cognitive health can improve significantly through reminiscence therapy. Studies suggest that reflecting on past experiences enhances memory and helps individuals maintain mental clarity. This process allows seniors to practice recalling essential events, names, and faces, which keeps their cognitive faculties sharp. Regular engagement with this therapeutic practice reduces the risk of cognitive decline and may delay the progression of Alzheimer's disease or dementia.
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